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The proteolytic enzyme, bromelain, or bromelin, was formerly derived from pineapple juice; now it is gained from the mature plant stems salvaged when fields are being cleared. The yield of bromelain from stem juice is 2.15%. The enzyme is used like papain from papaya fortenderizing meat and chill proofing beer; is added to gelatin to increase its solubility for drinking; has been used for stabilizing latex paints and in the leather-tanning process. In modern therapy, it is employed as a digestive and for its anti-inflammatory action after surgery, and to reduce swellings in cases of physical injuries; also in the treatment of various other complaints.

Bromelain - An Overview 2008 NPR 7(4) 359-363

Bromelain 5p

Bromelain 17p

Bromelain- A Literature Review and Discussion of its Therapeutic Applications 1996

Bromelain- A Literature Review and Discussion of its Therapeutic Applications

Bromelain- biochemistry, pharmacology and medical use

Bromelain induces cardioprotection against ischemia-reperfusion injury through Akt-FOXO pathway

Bromelain Monograph 4p

Bromelain Monograph 8p

Bromelain Reversibly Inhibits Invasive Properties of Glioma Cells

Extraction, purification and estimation of Bromelain V34-2Art3 pp67-76

In vitro study of bromelain activity in artificial stomach juice and blood

Purification and Characterization of Purification and CharacterizationBromelain J Biochem-1976-YAMADA-1223-34

References on BROMELIAN

Stability of bromelain-polyphenol complex in pineapple juice

Stem bromelain in cancer therapy

Stem Bromelain-A New Protease Preparation from Pineapple Plants

Therapeutic Application of Pineapple Protease (Bromelain)- A Review

Thermal stability of free bromelain and bromelain-polyphenol complex in pineapple juice

Using Bromelain in Pineapple Juice to Investigate Enzyme Function


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Pineapple Research Station
Kerala Agricultural University
Ernakulam Kerala 686670